{"id":274,"date":"2024-10-11T09:02:37","date_gmt":"2024-10-11T00:02:37","guid":{"rendered":"https:\/\/www.bio-sys.co.jp\/science-project\/?page_id=274"},"modified":"2025-09-26T17:37:59","modified_gmt":"2025-09-26T08:37:59","slug":"fullerticle-en","status":"publish","type":"page","link":"https:\/\/www.bio-sys.co.jp\/science-project\/fullerticle\/fullerticle-en","title":{"rendered":"Fullerticle"},"content":{"rendered":"\n<p>Water-soluble Fullerenes (Fullerticle) according to the industrial applications expanded through collaborative research with Tohoku University and Sendai National College of Technology.<\/p>\n\n\n\n<p>The water solubility of C<sub>60<\/sub> is imparted by encapsulating it with cyclodextrin (CyD). We succeeded in the mass production of Fullerticles by 3D ball mill.<\/p>\n\n\n\n<p>Due to the origin of the C<sub>60<\/sub>\u2019s absorption in visible region, fullerticle has a distinctive purple color.<\/p>\n\n\n\n<p>Fullerticle is composed of the safer chemicals. Further, the final products have been passed in the \u201catopic predisposition patch tested\u201d.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Anti-aging care<\/li>\n\n\n\n<li>Scalp care<\/li>\n\n\n\n<li>Tone up<\/li>\n\n\n\n<li>Sunscreen<\/li>\n\n\n\n<li>Moisturizing Rehydration<\/li>\n\n\n\n<li>For sensitive skin<\/li>\n<\/ul>\n\n\n\n<p>etc&#8230;for various products<\/p>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">UV protection of fullerticle<\/h2>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"521\" src=\"https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_sp_en-2-1024x521.png\" alt=\"\" class=\"wp-image-285\" srcset=\"https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_sp_en-2-1024x521.png 1024w, https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_sp_en-2-300x153.png 300w, https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_sp_en-2-768x391.png 768w, https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_sp_en-2.png 1335w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>In the UV-Vis absorption spectra of fullerticle solution, the characteristic peaks are observed in the UV region (UV-A ~ UV-C) as the spectra of fullerene C<sub>60<\/sub>, which means that fullerticle has UV protection.<\/p>\n\n\n\n<p>Based on the UV-protective properties of fullerticle derived from fullerene C<sub>60<\/sub>, fullerticle protects the skin from UV rays and reactive oxygen species.<\/p>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Observation with UV indicator<\/h3>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"276\" src=\"https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_in_en-1024x276.png\" alt=\"\" class=\"wp-image-286\" srcset=\"https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_in_en-1024x276.png 1024w, https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_in_en-300x81.png 300w, https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_in_en-768x207.png 768w, https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/uv_in_en.png 1329w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>As the results of UV protection measurements using  a commercially available  UV indicator, no UV was transmitted and sensed to the fullerticle solution&#8217;s specimens.<\/p>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Antioxidant activity measured by ESR<\/h2>\n\n\n\n<p>Radical scavenging activities of the fullerticle, having scavenging activity against hydroxyl radicals, were exhibited approximately to 7 times higher than those of tomatoes.<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes has-small-font-size\"><table><thead><tr><th class=\"has-text-align-center\" data-align=\"center\"><strong>Test case<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>Unit<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>Measured value<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>DB Average<\/strong><\/th><\/tr><\/thead><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\">Antioxidant capacity (plant stress tolerance)<\/td><td class=\"has-text-align-center\" data-align=\"center\"><\/td><td class=\"has-text-align-center\" data-align=\"center\"><\/td><td class=\"has-text-align-center\" data-align=\"center\"><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"> superoxide scavenging (activity value\uff09<\/td><td class=\"has-text-align-center\" data-align=\"center\">Units SOD\/g<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.6<\/td><td class=\"has-text-align-center\" data-align=\"center\">6.2<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><mark>Hydroxyl radical\nscavenging activity value<\/mark><\/td><td class=\"has-text-align-center\" data-align=\"center\"><mark>\u03bc mol DMSO\/g<\/mark><\/td><td class=\"has-text-align-center\" data-align=\"center\"><mark>3,890<\/mark><\/td><td class=\"has-text-align-center\" data-align=\"center\"><mark>527<\/mark><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Value of singlet oxygen removal activity <\/td><td class=\"has-text-align-center\" data-align=\"center\">\u03bc mol Histidine\/g<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.7<\/td><td class=\"has-text-align-center\" data-align=\"center\">105<\/td><\/tr><\/tbody><\/table><figcaption class=\"wp-element-caption\">DB average based on 122 tomato samples<\/figcaption><\/figure>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Product overview<\/h2>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"728\" height=\"238\" src=\"https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/image.png\" alt=\"\" class=\"wp-image-288\" style=\"width:300px\" srcset=\"https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/image.png 728w, https:\/\/www.bio-sys.co.jp\/science-project\/wp-content\/uploads\/2024\/10\/image-300x98.png 300w\" sizes=\"auto, (max-width: 728px) 100vw, 728px\" \/><\/figure>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">\u25a0<strong>Fullerticle particle solution<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-table is-style-stripes has-small-font-size\"><table><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Product name<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>Fullerticle particle solution<\/strong><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Feature<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">Fullerene C<sub>60<\/sub>-cyclodextrin complex nanoparticles\n(Fullerticle particles) dissolved in aqueous solution <\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>INCI name<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">Fullerences \/ Cyclodextrin \/ Water<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Amount of \nproduct<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">200ml \/ 50ml<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Nature<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">purple transparent solution \/ odorless<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Applications<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">Cosmetics<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Properties<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">\u00a0Antioxidation \/ antimicrobial skin conditioning<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Stock and preservation<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">Dark room temperature \/ bronzed light resistant container<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">\u25a0<strong>Fullerticle powder<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-table is-style-stripes has-small-font-size\"><table><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Product name<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>Fullerticle powder<\/strong><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Feature<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">Fullerene C<sub>60<\/sub>-cyclodextrin complex powder<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>INCI name<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">Fullerences \/ Cyclodextrin <\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Amount of \nproduct<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">500mg \/ 125mg<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Nature<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">\u00a0purple solid \/ odorless<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Applications<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">Cosmetics<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Properties<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">\u00a0Antioxidation \/ antimicrobial skin conditioning<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Stock and preservation<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">\u00a0Cool dark place (&lt; 10\u2103) \/ bronzed light resistant container<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-50 is-style-fill\"><a class=\"wp-block-button__link has-contrast-background-color has-background wp-element-button\" href=\"https:\/\/www.bio-sys.co.jp\/infomail.html\" target=\"_blank\" rel=\"noreferrer noopener\">Contact<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Water-soluble Fullerenes (Fullerticle) according to the industrial applications expanded through collaborative [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":335,"parent":44,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-274","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Fullerticle - \u682a\u5f0f\u4f1a\u793e\u30d3\u30aa\u30b7\u30b9<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.bio-sys.co.jp\/science-project\/fullerticle\/fullerticle-en\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fullerticle - \u682a\u5f0f\u4f1a\u793e\u30d3\u30aa\u30b7\u30b9\" \/>\n<meta property=\"og:description\" content=\"Water-soluble Fullerenes 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